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History

  THE EARLY HISTORY OF THE INRC (1969-1975)
  by the late Dr. Sydney Archer

In July 1969 the triennial meeting of IUPHAR was held in Basel. Right after the formal termination of the proceedings of that meeting a satellite session on narcotics was held in a classroom of the campus of the University on July 19, 1969, which is almost precisely 25 years ago. The facilities left something to be desired, but the session itself was lively and interesting. This meeting was planned and organized by Hans Kosterlitz and the late Harry Collier. The program had no papers on peptides, none on receptors and no mention of the term opioids which had not yet been coined by the late Bill Martin.

At the close of the proceedings which occupied all of one very hot and humid day morning the participants proceeded to have lunch as guests of the organizers at the Hotel Euler which according to the Guide Michelin had the best table in Basel. The entire budget for this meal was about 50 francs. I don't think that this sum will cover a lunch for two at the restaurant today. At the end of the meal there was a mild crisis when there was an unexpected distribution of excellent Havana cigars. Dr Kosterlitz realized immediately that unless unchecked this would be a budget-buster and he scurried around retrieving the distributed cigars before any of us could light up.

This meeting in Basel was actually a tryout for the big event which took place in 1971 at the University of Aberdeen. A symposium on narcotics and narcotic antagonists was held as part of the program of the annual meeting of the British Pharmacological Society. A volume entitled "Agonist and Antagonist Actions of Narcotic Analgesics" edited by Kosterlitz, Collier arid Villareal was published to commemorate the occasion.

In 1972 the IUPHAR met in San Francisco. Avram Goldstein organized a satellite session on narcotics which was held after the end of the formal meeting. Although this meeting was not as grand an occasion as the 1971 meeting it was highly significant in the sense that it demonstrated that investigators in the field that they would like to have an annual meeting devoted solely to narcotics.

In 1973 the group met at the University of North Carolina as a satellite to the CPDD meeting. It was clear that our organization was outgrowing its infancy and it was time to be baptized. The name originally given was The International Narcotics Research Club. There was no problem accepting the words International and Research, but Harry Collier preferred the singular form Narcotic to the plural. This suggestion was not accepted. The word Club provoked the most discussion. The pro-Club advocates contended that since there was a Histamine Club and a Catecholamine Club, why not a Narcotic Club? The anti's felt that Club implied something elitist and preferred something else. The antis won out, not because of the persuasiveness of their arguments, but because Steve Szara of NIDA informed us that if we ever wanted to obtain financial support from NIDA for future meetings, we had better drop the word Club. What could be substituted for Club and still maintain the acronym INRC? Eric Simon came to the rescue with the suggestion "Conference" and the International Narcotics Research Conference is what we have been ever since.

In 1974 the CPDD met in Mexico City. There was a tremendous consumption of Lomotil at that meeting and we have Paul Jannsen, its developer, to thank for keeping attendance at the scientific sessions at a respectable level. Julian Villareal who left the University of Michigan to return to his homeland arranged for the INRC to meet in Cocoyoc, about a two hour bus ride from Mexico City. At the end of the last paper of the last of our sessions, Hans Kosterlitz dropped a bombshell when he casually announced that he and John Hughes had isolated an unstable material from mammalian brain which behaved pharmacologically like morphine.

In 1975, the INRC met at the Airley House in Virginia after the CPDD meeting which was held in Washington. At that meeting an Executive Committee was formed and Avram Goldstein was formally installed as Secretary. Also a set of by-laws were drawn up which apparently was written in invisible ink. A nomenclature brouhaha occurred at a lunch table one day. Among those present were Goldstein, Kosterlitz and Simon. Avram protested that the name enkephalins was too restrictive to be used as a generic name for opioid peptides. Hans countered with the assertion that the discoverer had the right to name his discovery. Finally after a prolonged discussion Eric Simon came to the rescue again. He suggested the term "Endorphine" as a contraction of endogenous morphine. Avram suggested that the final "e" be dropped. That is the origin of the term "endorphin".

After the 1976 meeting it was clear that the INRC was going to enjoy vigorous growth. When I succeeded Avram as Secretary, membership numbered between 100 and 200. When I turned the records over to my successor Eric Simon, the mailing list contained over 400 names. It was the early efforts of Kosterlitz, Collier and Goldstein that contributed the most to making the INRC the thriving institution which it is now on the occasion of its 25th birthday.

    History of INRC Meetings (early dates/names kindly provided by Dr. Eric Simon)

Dates Venue INRC President Program/Local
Chairperson(s)
7/19/1969 Basel, Switzerland H. Collier, H.Kosterlitz Same as Execs
1971 Aberdeen, Scotland H. Kosterlitz Same
7/29/1972 San Francisco, CA, USA A. Goldstein Same
1973 Chapel Hill, NC, USA A. Goldstein Same
3/14-3/16/1974 Cocoyoc, Mexico A. Goldstein Same
5/21-5/24/1975 Airlie House, VA, USA A. Goldstein Same
7/19-7/22/1976 Aberdeen, Scotland S. Archer H. Kosterlitz
6/28-7/02/1977 Brewster Acad., NH, USA S. Archer E. Simon
(Gordon Conf)
7/23-7/27/1978 Noordwijkerhout, Netherlands S. Archer J. Van Ree,
L. Terenius
6/11-6/15/1979 Seacrest Hotel,
N. Falmouth, MA, USA
S. Archer E.L. Way
6/23-6/27/1980 Plymouth State College, NH (Gordon Conf.) E. Simon Same as Exec
7/26-7/30/1981 Kyoto, Japan E. Simon H. Takagi
6/14-6/18/1982 Seacrest Hotel,
N. Falmouth, MA
E. Simon B. Cox,
A. Takemori
6/26-7/01/1983 Garmisch, Germany E. Simon A. Herz
7/22-7/27/1984 Cambridge,England E.L. Way J. Hughes
6/23-6/28/1985 Seacrest Hotel,
N. Falmouth, MA
E.L. Way A. North
6/06-6/11/1986 Marriott Airport,
San Francisco, CA
E.L. Way H. Loh
8/31-9/04/1987 Adelaide, Australia E.L. Way S. Johnson
7/03-7/08/1988 Albi, France A. Herz J. Cros,
J-C. Meunier
7/09-7/14/1989 St. Adele, Canada A. Herz R. Quirion,
K. Jhamandas,
C. Gianoulakis
1990 Noordwijkerhout, Netherlands A. Herz J. Van Ree
6/30-7/05/1991 Copper Mountain, CO
(with FASEB)
H. Akil T. Burks, B. Cox,
J. Holaday
7/24-7/27/1992 Keystone, CO,
(with CPDD)
H. Akil H. Akil
7//10-7/15/1993 Skövde, Sweden H. Akil F. Nyberg
7/16-7/21/1994 Seacrest Hotel,
N. Falmouth, MA, USA
H. Akil E. Simon
7/09-7/14/1995 University of St. Andrews
St. Andrews, Scotland
B. Cox J. Traynor
7/21-7/26/1996 Queen Mary Ship
Long Beach, CA
B. Cox S. Watson
8/03-8/08/1997 Hong Kong, China B. Cox T. Wong,
H. Loh
7/20-7/25/1998 Congress Center, Garmisch-Partenkirchen,
Germany
B. Cox V. Höllt
6/10-6/15/1999 Saratoga Springs Sheraton,
Saratoga Springs, NY, USA
C. Chavkin S. Childers,
J. Bidlack
7/15-7/20/2000 University of Washington,
Seattle, WA, USA
C. Chavkin C. Chavkin
7/14-7/19/2001 Marina Congress Center
Helsinki, Finland
C. Chavkin E. Kalso,
L. Ahtee
7/9-7/14/2002 Asilomar (with ICRS)
Monterey, CA, USA
C. Chavkin C. Evans,
L. Toll
7/6-7/11/2003 Palais des Congrès
Perpignan, France
M.J. Kreek B. Kieffer,
P. Jauzac
July 18-23, 2004 Kyoto Park Hotel Kyoto, Japan
M.J. Kreek H. Ueda,
M. Satoh
July 10-15, 2005 Marriot on the Harbor
Annapolis, MD USA
M.J. Kreek George Uhl,
Jai-Bei Wang
July 9-14, 2006 St. Paul Radisson
St. Paul, MN, USA
M.J. Kreek Ping-Lee Law,
George Wilcox
July 8-13, 2007 Freie Universität Berlin
Berlin, Germany
L. Devi Christoph Stein
July 13-17, 2008 Francis Marion Hotel
Charleston, SC, USA
L. Devi Jakie McGinty
July 12-17, 2009 Benson Hotel
Portland, OR, USA
L. Devi John Williams
Susan Ingram
July 11-16, 2010 Hilton Hotel
Malmö, Sweden
L. Devi Fred Nyberg
June 21-25, 2011 Westin Diplomat Hotel
(with CPDD)
Hollywood, FL, USA
J. Traynor Sari Izenwasser
Ellen Unterwald
July 14-20, 2012 Sheraton Crown Center
Kansas City, MO, USA
J. Traynor Tom Prisinzano
July 14-18, 2013 Sebel Hotel
Cairns, North Queensland, Australia
J. Traynor Mark Connor
Mac Christie
July 13-18, 2014 Hilton Montreal Bonaventure
Montreal, Canada
J. Traynor Louis Gendron
June 15-20, 2015 Biltmore Hotel
(with CPDD)
Pheonix, Arizona, USA
F. Nyberg Todd Vanderah
July 10-14, 2016

Bath Assembly Rooms,
Bath,
England, UK

F. Nyberg Chris Bailey et al.
July 9-14, 2017 Hyatt Magnificent Mile Hotel, Chicago IL, USA F. Nyberg Amynah Pradhan
June 12-16, 2018

Hilton Bayfront Hotel
(overlap with CPDD)
San Diego, CA USA

F. Nyberg Larry Toll
July, 2019 50th anniversary meeting!
New York, NY USA
TBN Mary Jeanne Kreek, Lakshmi Devi
July, 2020 TBA TBN TBN

INRC Executive Committee Membership: Since 1992 

MTG
YEAR

President

Pres-Elect

Past-Pres

Treasurer

North America representatives   

Europe representatives  

Rest of World representatives

2019 TBN   Nyberg Toll Al-Hasani Zadina TBN Schulz Hipolito TBN Tokuyama Canals TBN
2018 Nyberg TBN Traynor Toll Al-Hasani Zadina Pradhan Schulz Hipolito Bailey Tokuyama Canals Ikeda
2017 Nyberg Traynor Toll Cahill Zadina Pradhan Stein Hipolito Bailey Bigliardi Canals Ikeda
2016 Nyberg Traynor Toll Cahill Moron-Concepion Pradhan Stein Massotte Bailey Bigliardi Pick Ikeda
2015 Nyberg Traynor Toll Cahill Moron-Concepion Prisinzano Stein Massotte Koch Bigliardi Pick Sora
2014 Traynor Nyberg Devi Toll McLaughlin Moron-Concepion Prisinzano Husbands Massotte Koch Bagley Pick Sora
2013 Traynor Devi Toll McLaughlin Ingram Prisinzano Husbands Nylander Koch Bagley Chiou Sora
2012 Traynor Devi Bidlack McLaughlin Ingram Gendron Husbands Nylander Milligan Bagley Chiou Kishioka
2011 Traynor Devi Bidlack Unterwald Ingram Gendron Kitchen Nylander Milligan Connor Chiou Kishioka
2010 Devi Traynor Kreek Bidlack Unterwald Traynor Gendron Kitchen Schulz Milligan Connor Tao Kishioka
2009 Devi Kreek Bidlack Unterwald Traynor Carroll Kitchen Schulz Nyberg Connor Tao Narita
2008 Devi Kreek Bidlack Lei Yu Traynor Carroll C. Stein Schulz Nyberg Christie Tao Narita
2007 Devi Kreek Bidlack Lei Yu Standifer Carroll C. Stein Maldonado Nyberg Christie Ueda Narita
2006 Kreek Devi Chavkin Bidlack Lei Yu Standifer Shippenberg C. Stein Maldonado Kitchen Christie Ueda Kamei
2005 Kreek   Chavkin Bidlack Liu Chen Standifer Shippenberg Zimmer Maldonado Kitchen Ji-Sheng Han Ueda Kamei
2004 Kreek   Chavkin Simon Liu Chen Portoghese Shippenberg Zimmer Höllt Kitchen Ji-Sheng Han Vogel Kamei
2003 Kreek   Chavkin Simon Liu Chen Portoghese Uhl Zimmer Höllt Jauzac Ji-Sheng Han Vogel Ueda

2002

Chavkin

Kreek

Cox

Simon

Toll

Portoghese

Uhl

Maldonado

Höllt

Jauzac

Gang Pei

Vogel

Ueda

2001

Chavkin

 

Cox

Simon

Toll

Zadina

Uhl

Maldonado

Paakkari

Jauzac

Gang Pei

Christie

Ueda

2000

Chavkin

 

Cox

Simon

Toll

Zadina

Childers

Maldonado

Paakkari

Kieffer

Gang Pei

Christie

Suzuki

1999

Chavkin

 

Cox

Simon

Evans

Zadina

Childers

Borsodi

Paakkari

Kieffer

Wong

Christie

Suzuki

1998

Cox

Chavkin

Akil

Simon

Evans

Devi

Childers

Borsodi

Kitchen

Kieffer

Wong

Vogel

Suzuki

1997

Cox

 

Akil

Way

Evans

Devi

Leslie

Borsodi

Kitchen

Nyberg

Wong

Vogel

Ueda

1996

Cox

 

Akil

Way

Kreek

Devi

Leslie

Meunier

Kitchen

Nyberg

Pilcher

Vogel

Ueda

1995

Cox

 

Akil

Way

Kreek

Chavkin

Leslie

Meunier

Przewlocki

Nyberg

Pilcher

Simantov

Ueda

1994

Akil

Cox

Herz

Way

Kreek

Chavkin

Sadee

Meunier

Przewlocki

Nyberg

Pilcher

Simantov

Nazaki

1993

Akil

 

Herz

Way

Porreca

Chavkin

Sadee

Meunier

Przewlocki

Traynor

Pilcher

Simantov

Nazaki

1992

Akil

 

Herz

Way

Porreca

Jhamandas

Sadee

Mulder

Roques

Traynor

Han

Johnson

Nazaki

 

 

 

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